sterile, isotonic 0.9% sodium chloride solution designed specifically as a diluent for the safe reconstitution of botulinum-toxin type A (e.g., Botox) and other injectable preparations.
Full version: This single-use, aseptic saline solution provides the correct isotonic vehicle for dissolving botulinum-toxin powder, facilitating accurate dosing, maintaining product stability and ensuring patient safety. With a body-compatible sodium chloride concentration (0.9%), it allows practitioners to tailor dilution volumes according to treatment area, while minimizing tissue irritation and preserving toxin efficacy.

0.9% Non-Preserved Saline Solution: The Essential Diluent for BOTOX® Injections

Unlock the full potential of your neuromodulator treatments with our premium 0.9% Non-Preserved Saline Solution, specifically formulated for the precise reconstitution of Botulinum Toxin Type A products, such as BOTOX®, Dysport®, and Xeomin®.

Why Choose Our Saline for Your Practice?

Optimal Purity & Safety: Manufactured to the highest standards, our non-preserved 0.9% Sodium Chloride solution meets the rigorous demands for injectable preparations. The non-preserved nature ensures compatibility and minimizes the risk of local irritation at the injection site.

Precise Reconstitution: Achieve the exact dilution ratio recommended by the manufacturer. Correct reconstitution is critical for accurate dosing, predictable results, and maximum product efficacy. (Where to buy saline for injection)

Versatile Volume Options: Available in a range of sizes to suit the needs of your practice, from individual treatment vials to larger volume bottles for busy clinics.

Professional Standard: An indispensable component for all practitioners—including dermatologists, plastic surgeons, and aesthetic nurses—who require a reliable and high-quality diluent for their cosmetic and therapeutic neurotoxin procedures.

Ensure accurate dosing and smooth preparation for every BOTOX® injection. Trust the essential diluent relied upon by professionals.

Key Features & Benefits

Feature-first bullet list

• 0.9% Sodium Chloride (NaCl) – isotonic vehicle: Matches physiological salinity, reducing risk of tissue irritation when injecting.
• Sterile, preservative-free (unless otherwise stated): Complies with manufacturer reconstitution guidance (for example, the official Botox Instructions for Use require “sterile un-preserved normal saline (0.9% sodium chloride for injection)”.)
• Optimised for botulinum-toxin reconstitution: Ensures that your botulinum-toxin powder is dissolved into a suitable vehicle that maintains potency and dosing accuracy.
• Single-use or single-patient ampoule / syringe format: Minimises risk of contamination and supports compliance with standard protocols. For example, one product description states: “Comes in a 5 mL ampoule for single-use, minimizing waste and contamination risk.”
• Clear, colourless solution: Upon reconstitution and injection, should be free from particulate matter and visually transparent, assuring quality.
• Flexible dilution volumes: Enables the professional to adjust the final concentration of toxin per 0.1 mL for fine versus larger-muscle injections (e.g., more saline = lower concentration for superficial areas; less saline = higher concentration for deeper muscles).

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By using this saline solution, aesthetic medicine professionals ensure that their botulinum-toxin procedures begin with a reliable, body-compatible vehicle. This supports:

• Precise dosing and predictable results (reducing risk of under- or overdilution).
• Better patient comfort — isotonic saline tends to cause less stinging than hypotonic diluents.
• Compliance with standard reconstitution protocols — helping to safeguard toxin potency and patient safety.
• Operational efficiency — pre-measured, ready-to-use packaging reduces preparation time and risk of error.

Technical & Logistics Specifications

• Form: Clear, colourless sterile solution
• Concentration: 0.9% sodium chloride (NaCl) in Water for Injection (WFI)
• Packaging: e.g., 5 mL single-use ampoule (alter if your pack size is different)
• Storage: Store at temperatures not exceeding 30 °C (or per your product’s label). Protect from light. Do not freeze. (Example: “Store in a sealed container at temperatures not exceeding 30 °C.”)
• Shelf-Life: 36 months from manufacture (example specification)
• Usage: For professional use only — to be used by licensed healthcare practitioners experienced in botulinum-toxin injections.
• Single-use: Once the ampoule is opened or withdrawn, discard any unused portion. Do not reuse.
• Compatibility: Suitable diluent for botulinum-toxin type A products (e.g., Botox), and other injectable powders requiring isotonic saline reconstitution.

Usage Guidance

Important: This product is intended for use only as the reconstitution vehicle for injectable powders (such as botulinum-toxin type A) by qualified healthcare professionals. It is not for direct injection as a stand-alone therapy.

1. Clean the vial stopper of the toxin powder with 70% alcohol and allow to dry. (Medicines.org.uk)
2. Using a sterile syringe, draw the required volume of this saline solution (volume will depend on desired concentration). For example: a common dilution of Botox is with 0.9% saline (e.g., 10 mL for a 100-unit vial yields 10 units per 0.1 mL) depending on indication.
3. Insert the diluent gently into the vial of powder — do not swirl vigorously or shake, as this may denature the toxin protein. Gently rotate until fully dissolved.
4. Inspect the resulting solution: it should be clear, colourless to slightly yellow, and free from particulate matter.
5. Use the reconstituted toxin within the timeframe recommended by the toxin manufacturer (often within 24 hours when stored at 2-8 °C).
6. Discard any unused reconstituted solution or any remaining saline that has been punctured/opened.

Q&A / FAQ

Q 1. Why 0.9% saline and not water or other diluent?
Because isotonic 0.9% sodium chloride matches body fluid osmolality, reducing the risk of cell damage, irritation, or altered toxin diffusion. Manufacturer product information for botulinum-toxin states use of “sterile un-preserved normal saline (0.9% sodium chloride for injection)”.

Q 2. Can bacteriostatic saline (with benzyl alcohol) be used?
It depends on local regulation and toxin manufacturer recommendations. Some practitioners prefer bacteriostatic saline for multi-patient use because of the antimicrobial effect of benzyl alcohol, but care must be taken because the toxin manufacturer may specify preservative-free diluent.
Note: If you market the product, be clear about whether it is preservative-free or contains preservatives.

Q 3. What dilution volumes should be used?
That depends on the indication and target area. For example, the SmPC for Botox provides a table: for a 100-unit vial, adding 10 mL saline results in a concentration of 10 units per 0.1 mL.  Smaller volumes yield higher concentrations (more units per 0.1 mL) for deeper muscle injections; larger volumes yield lower concentration for superficial areas. Always follow the toxin manufacturer’s protocol and your local standards of care.

Q 4. Who should use this product?
Licensed and trained healthcare professionals (dermatologists, plastic surgeons, nurse practitioners with credentialing) trained in botulinum-toxin injections and aseptic technique. Not for self-administration.